Extremely, what is all this additional glucose, & how is it so harmful to our health? To grasp this, we must first grasp the fundamentals. The basic components of added sugars are two basic sugars named “glucose” and “fructose.”
While those basic carbohydrates are chemically identical, they are processed in the system by separate mechanisms.
The Dangers Of Too Much Fructose
Although it has become established that excess sugar consumption (even within “normal” levels) is hazardous to our health, the fundamental processes governing sugar conversion and their possible role in metabolism diseases are still unknown.
In today’s quick society, there is a growing reliance on readily accessible “quick” foods and drinks. Such products are usually lacking in fiber and key vitamins, and they generally have a lot of sugar added to them.
The growth in metabolic illnesses such as diabetes, hyperlipidemia, and cardiovascular disease has been linked to this change in nutritional patterns, which has been followed by inactive lifestyles.
The problem with sweets is that however you consume it, the more you want it, which can lead to a vicious circle of overeating and ill health. Many people prefer to have sweet food items in different forms.
One must know that in all such items fructose is an element contained and too much of it present in the body may lead to various health complications including diabetes.
This can be troublesome if one gets it at a young age as it may not lead to other health disorders but also affect the overall life expectancy. The research was carried on different samples with consumption of various food items that had fructose in them in different forms and with different age groups as well as areas of living and backgrounds.
As the sugar reaches the bloodstream, the kidney or liver, both key metabolic centers in our bodies, keep it at distance (albeit at a much lower level than glucose).
Glucose is diverted for sugar generation in these tissues through a mechanism known as “gluconeogenesis.” However, this reaction requires the breakdown of a molecule called “ATP”(Adenosine triphosphate).
Thus, an excessive intake of fructose can lead to ATP (Adenosine triphosphate)depletion in cells, which activates another pathway involved in uric acid metabolism leading to an accumulation of uric acid in the blood and joints and increasing the risk of developing “gout”.
Glucose intake also can cause a rise in cholesterol and belly obesity, raising the danger of cardiovascular disease, according to experts.
In a thorough examination released in a famous Medical Journal, Chinese scholars aimed to understand the destiny of eating fructose in the brain and the processes that regulate its metabolism.
Prof. Weiping J. Zhang, the paper’s senior writer, says, “Our review provides a comprehensive update on the progress on molecular and cellular aspects of fructose metabolism and their role in the development of metabolic diseases. These findings can aid the development of new diagnostic, preventative, and therapeutic strategies for metabolic diseases.”
Nevertheless, the chemical factors that regulate ChREBP activity in reaction to sugar stimulus are yet unknown. Prof. Zhang elucidates: “Obtaining a better understanding of the biochemical regulatory mechanism of ChREBP pathway can definitely provide new clues into the regulation of fructose metabolism and its metabolic effects. Future advances in this field will benefit our efforts to achieve better cardiometabolic health and inform clinical recommendations on the dietary intake of the sugar.”
Altogether, these data show how such an increase in sugar intake can produce an unbalance in multiple biochemical systems in the brain, which can result in illness. Whatever we consume does, in fact, have a significant impact on our overall wellness.
