At Baylor College of Medicine, a study was conducted by the researchers in which patients reported the outcomes to evaluate the efficacy of platelet-rich plasma (PRP) treatment in osteoarthritis (OA).
In the journal regenerative medicine, the result has been published in which it has shown that a single injection of leukocyte-rich/PRP in the knee joint which shows great improved functional mobility, pain in the joint, and the quality of life after six weeks of taking an injection.
Platelet-Rich Plasma Treatment Shows Efficacy For Osteoarthritis
From our study, in a large no. of clinics also this approach of musculoskeletal disorders biological therapies are used for evaluation trials. Those who are above 55 suffer from osteoarthritis in most cases.
The expert team has carried out research on people who suffer from this disease and offered them plasma treatment, which is one of the parts of the medical options used for various ailments presently, and found some encouraging results in most of the patients who were offered this treatment.
The treatment is easy to carry out compared to other options used for this ailment and also takes less time to deliver the desired results stated a member of the research team.
Nearly 52 million Americans are affected by this disability in which osteoarthritis (OA) is the main cause said author Dr. PrathapJayaram, who is the director of regenerative sports medicine and also an assistant professor in the department of physical medicine and rehabilitation and orthopedic surgery at Baylor.
From the study, it has been calculated that more than 80 percent of the population, people who are older than 55 years are carrying a kind of X-RAY –based evidence of diseases.
In our body, where the smooth muscle lie between the bones and cartilage breaks down and due to OA develops. Afterward slowly, the joints will become swollen and painful to move explained by Jayaram.
In the current situation, there are no valid therapies that can eradicate this disease progression. But, with the help of corticosteroid, a kind of symptom is alleviating. Although steroids seem to be helpful for the short term to get relief from pain in the joint. With long-term steroid use, you may get relief from pain in the joint but, you will suffer from loss of cartilage too as said by Jayaram.
As Osteoarthritis (OA) is particularly a joint disease there is a need for novel therapy required which can eradicate its flow of symptoms from its root joint. While in search of functional outcomes PRP has emerged as one of the life savvier which, can be used in the treatment of people with OA. PRP is being widely used treatment in clinical practices.
In this PRP therapy, a new challenge has been shown, in which Jayaram said this therapy will be based on the patient-reported outcome. The report will assess pain or moment of joint, such as how much quicker you are getting up from chair called time-up-and-go. This outcome will thoroughly evaluate the efficiency of PRP in knee joint OA.
PRP treatment is done by preparing PRP from the patient’s own blood. In the blood of the patient, red blood cells will get removed and platelets concentration will be enriched. PRP is formulated with leukocyte-rich (LR) and leukocyte-poor (LP).
A study by Jayaram shown that LR-PRP had effective disease-modifying outcomes. Currently estimated that a single injection of LR-PRP in the knee can bring improvement in knee function, mobility, relief from swelling, and get a quality life with good function of joints after six weeks of getting injected in the knee.
This study provides the basis to conduct a large number of clinical trials of PRP in current days.
