In recent decades, the term “genomics” is becoming a buzzword, particularly as it is rapidly being employed in clinical settings, whereas proteomics is still rather mysterious to many individuals.
According to some experts in this field, some more information can help one know many more things about human health and various elements. This is why several institutes and experts have started research on this aspect that can help the experts know hidden facts about proteome.
What Do We Know About Proteome?
Proteomics is the study of how proteins work and connect with each other—recognizing how protein molecules interact with one another aids in the comprehension of illnesses. Significantly, the majority of history’s medications seem to be either protein or specifically target protein molecules. As per experts, there are many things yet to be known about this aspect, and if they are known, the treatment options can be changed to support the health of many individuals who suffer from different diseases. Some more research in this field is a need for a time now.
The gene is largely consistent or static, inside the sense that it is basically just the same as well as also only alters whenever a mutant allele, but the proteome is active. It evolves over time and therefore is impacted by the immune system’s needs and pressures.
Distinct tissues, for instance, create different combinations of protein, as well as somehow, this fluctuates over time so that it might be various in the day versus the evening. Proteomic methods can help us comprehend an individual more, particularly if used in conjunction with additional so-called ‘omic’ technology like genetics.
Just like Dr. Huang argues, the seven blind men and the elephant are analogous.
“Consider seven blind guys that have never seen elephants struggling to sort out what appears like by touching various sections of an elephant’s body.
“If you only touch one section of an elephant at the moment, you won’t realize it’s an elephant,” as the saying goes, and the same might be said about omic technology. You won’t obtain a comprehensive understanding of cancer if you only use genetics. However, if you combine diverse data sources, such as proteomics, you’ll get a lot better, more complete picture.”
Professor Jyoti Choudhary is the Head of Proteomics at the ICR and oversees the proteomics laboratory, which does protein testing for ICR scientists.
Professor Choudhary and her colleagues are also interested in learning more about how the organization and stability of protein systems contribute to melanoma’s capacity to develop and resist chemotherapy.
Professor Choudhary, with her colleagues, recently cooperated helped scientists at Imperial to identify how microbial proteins operate as a system to assume charge of human cells. The results taken by this can be used to identify the effect of microorganisms in the stomach in cancers, including intestinal cancer.
Dr. Huang’s study focuses on proteomics in order to better comprehend sarcomas, several of the uncommon cancers with high unmet demand.
Scientists could use proteome data to find proteins causing cancer. When scientists get this data, they may examine the protein’s system and create medications that block the protein’s effect.
Since it contains useful techniques for finding therapeutic targets, proteomics has — most importantly in assisting humans in treating cancer. Proteomics can assist in translating basic scientific findings into focused, more tailored therapies in this manner.
“Sarcomas are cancerous tumors that makeup 1% of all malignancies; they have unique genes and human biology because they are hard to cure.”
Dr. Huang, with his colleagues, will proceed to delve into biology to completely comprehend the protein mechanism that causes these diseases to develop new, more effective treatments.
