University of Utah health scientists are making efforts to find out if salivary glands are infected with the virus. That causes too COVID-19 could diminish the person’s long-term immunity for the disease after the immunized or else after recovering from the illness of the person.
The National Institute of Health supported two years for the investigation, will explore whether the salivary glands that have SARS-CoV-2 can lessen the body to make the ability to antibodies that would protect against the reinfection by the virus.
Can COVID-19 Cause Infection Of Salivary Glands And Worsen It?
Coronavirus has been nothing less than a mystery for researchers as many things are still unclear about this virus. Hence experts keep on carrying out various researches with the help of which some better cure for concerned disease can find out.
A team of specialists has studied the effects of this virus on salivary glands and checked if the virus causes any infection to the same. Though this virus is highly dangerous for the respiratory system, the study on salivary glands is still new in the field of research, and hence its conclusions are much important.
SARS-CoV-2 is a virus that is commonly found in the salivary glands. It is still a mystery that how the virus gets into the salivary glands. The virus will enter from the salivary glands through the moist inner line of an oral cavity is known as mucosa or else travel from the bloodstream, said Melodie Weller Ph.D. is an assistant professor of dentistry, he was leading the new study.
In the other parts of the body, salivary glands also have an” immune privilege,” which means if the glands are infected with the virus even though that the immune system won’t be affected within the glands.
As a result, the salivary glands won’t be affected by the viruses like SARS-CoV-2 and other viruses. For salivary glands, the immune power won’t be affected even they are affected by different viruses.
The proteins that are present in the digestive tract can trigger are known as “oral tolerance.” As a result, our immune system doesn’t develop the antibodies for these proteins like those foods that we eat, said Weller, because the virus contains the proteins that were overlooked by the immune system in the gastrointestinal tract.
“In the salivary glands, if the viral proteins are released, then the person gets a lot of salivae every day. That may also have the capability to decrease the antibodies”, said Weller. The viruses will not affect the salivary glands of the person if they are affected with SARS-CoV-2 and other viruses.
The research said that SARS-CoV-2 is released from the salivary glands, which may prevent the production of antibodies and also, from the research, increases the risk of relapse or reinfection. There is also a limit to the long-term effectiveness of a vaccine.
Weller and colleagues are expressing SARS-CoV-2 that produces the viral proteins in the salivary glands. They are planning to make a vaccination trial on animals. To know how the vaccine works on the animal’s health and the result in their salivary glands.
Weller said that if the viral proteins are developed in the guts of swallowing saliva, then it will slightly decrease in immunity or decrease in duration of the immune response.
The University of Utah health scientists started an investigation on if salivary glands infected with the viruses like SARS-CoV-2 and other viruses diminish the person’s long-term immune system to the disease after recovering from the illness of a person.
From the investigation, scientists stated that the SARS-CoV-2 is released from the salivary glands and produces antibodies and increases the risk of relapse or else reinfection.
