Alpha Brain Reviews – Should You Buy Onnit Memory & Focus Supplement?

Alpha BRAIN is a popular nootropic supplement from Onnit designed to support cognition, memory, mental speed, and focus.

Priced at $34.95 for a 15 day supply, Onnit Alpha BRAIN’s caffeine-free formula can aid mental processing, help with flow state, and promote focus, among other benefits.

Keep reading to find out everything you need to know about Onnit’s Alpha BRAIN and how the nootropic works today in our review.

What is Onnit Alpha BRAIN?

Onnit Alpha BRAIN is a nootropic, or brain boosting supplement, available online through

Featuring a blend of science-backed ingredients, Alpha BRAIN aims to be the ultimate way to help anyone enter “the zone.” By taking one serving of Alpha BRAIN daily, you can help your brain enter a flow state, giving you better memory, focus, and cognitive processing speed.

With over 1 million bottles sold to date, Alpha BRAIN is one of the bestselling nootropic supplements in the world.

As part of a 2023 promotion, Onnit is selling two and three bottle packages of Alpha BRAIN at a discounted rate. Plus, all purchases come with a free copy of Joe Rogan’s book, The Facts of Life.

Alpha BRAIN Benefits

According to Onnit, Alpha BRAIN can help support the following benefits:

  • Help mental processing
  • Caffeine-free
  • Help with flow state
  • Promote focus
  • Support memory
  • Focus on complex tasks, think clearly under stress, and react more quickly
  • The formula is also dairy-free, gluten-free, keto-friendly, nut-free, and paleo.

How Alpha BRAIN Works

Alpha BRAIN works using natural ingredients to support memory, flow, processing, and overall cognition.

Onnit makes a big deal of the supplement’s ability to help you enter a “flow” state. Sometimes, you feel like everything is going right for you. You have a perfect state of calm, focused energy. Your mind and body are perfectly in sync. Alpha BRAIN wants to help you enter that flow state and remain in it as long as possible.

Here’s how Onnit describes the effects of Alpha BRAIN:

“With its trademarked ingredient blends, Alpha BRAIN helps build an environment in which the brain can operate on all cylinders, promoting lasting mental clarity.”

To achieve these effects, Alpha BRAIN focuses on two pillars, including:

  • Method of Action #1: Getting your brain to make more alpha waves.
  • Method of Action #2: Supporting the production of neurotransmitters, or chemicals relaying information in and from the brain.

Onnit developed Alpha BRAIN with both of these goals in mind. Today, Alpha BRAIN uses science-backed ingredients to achieve the effects listed above, helping you boost brain power and support cognition in multiple ways.

Alpha BRAIN Ingredients

Alpha BRAIN contains a blend of plant extracts, amino acids, and other nutrients to support brain health and cognition in various ways.

Here are all of the active ingredients in each capsule of Alpha BRAIN and how they work:

L-Theanine: Part of Alpha BRAIN’s Flow Blend, L-theanine is an amino acid shown to stimulate the release of dopamine and serotonin in the brain. Many take L-theanine daily to put themselves in a state of “flow” – or calm focus. Dopamine and serotonin can also induce relaxation by stimulating alpha brain wave activity. The end result, according to Onnit, is L-theanine can promote attention and reaction time for meaningful results on cognition.

L-Tyrosine: Another amino acid, L-tyrosine can help the body produce adrenaline and dopamine. It’s been shown to aid cognitive performance in stressful situations. Like L-theanine, L-tyrosine can promote alpha brain wave activity, working to ensure your alpha waves are firing high for maximum productivity, motivation, energy, and focus. L-tyrosine is the second ingredient in the Alpha BRAIN Flow Blend.

Phosphatidylserine: Phosphatidylserine is a type of fat found in cell membranes. Many nootropics contain the ingredient because it plays an important role in cellular function – particularly in the brain. Phosphatidylserine is the third ingredient in the Alpha BRAIN Flow Blend.

Oat Straw Extract: Oat straw extract is a compound extracted from oats. Believed to promote overall cognitive function, oat straw extract is one reason why oatmeal is traditionally known as “brain food.” It’s the fourth and final ingredient in the Alpha BRAIN Flow Blend.

Cat’s Claw: Cat’s claw extract is one of the largest ingredients in Alpha BRAIN. The plant has a long history of use in South America. Today, the extract of the bark of the cat’s claw tree can purportedly boost cognition, support alpha wave activity, and ensure your brain remains in a calm state of focus.

Alpha GPC: Alpha GPC is the first ingredient in the Alpha BRAIN Focus Blend. Like other ingredients in the Focus Blend, alpha GPC is designed to promote optimal acetylcholine levels. Your brain produces acetylcholine, a valuable neurotransmitter, to control nerves, muscle cells, hormonal glands, and more. Alpha GPC specifically works because it contains a compound acting as a precursor to acetylcholine, aiding your body’s natural production of the neurotransmitter.

Huperzia Serrata: Alpha BRAIN contains clubmoss, also known as Huperzia serrata. The plant is naturally rich with Huperzine A. Huperzine A has been shown to help stop the breakdown of acetylcholine. After alpha GPC boosts your body’s production of acetylcholine, alpha GPC can keep your production high, leading to optimal acetylcholine levels overall.

Bacopa Monnieri: Bacopa monnieri is a perennial herb shown to help nerve signal reception by promoting nerve cell activity. Bacopa monnieri can promote the growth of the parts of nerve cells receiving messages from other nerves. Enhanced neve signalling can lead to better focus, memory, and overall cognition.

Vitamin B6: Vitamin B6 plays an important role in neurotransmitter production, and Alpha Brain contains nearly 6 times your daily value (DV) of vitamin B6. Vitamin B6 can help support the production of acetylcholine and other neurotransmitters linked to focus, energy, and cognition.

Pterostilbene: Pterostilbene is a derivative of resveratrol, the popular antioxidant molecule found in many supplements. Pterostilbene promotes cellular integrity, which can help maintain your brain and nerve cells. When your brain and nerve cells have more integrity, it can reduce breakdown and support cognition in multiple ways. Pterostilbene is the first of two ingredients in Onnit’s Fuel Blend.

L-Leucine: L-leucine is a branched chain amino acid, or BCAA, helping the body synthesize protein. As the second ingredient in the Onnit Fuel Blend, L-leucine can contribute to a healthy brain environment and optimal neural communication in the brain.

Alpha BRAIN Supplement Facts

Scientific Evidence for Alpha BRAIN

One of the cool things about Alpha BRAIN is that it’s one of the few nootropics backed by genuine clinical trials. Many nootropics contain individual ingredients that have been studied. However, Alpha BRAIN itself has been studied as a whole in formal, professional, double-blind, placebo-controlled scientific settings.

In a 2016 study published in Human Psychopharmacology, for example, researchers found Alpha BRAIN could enhance cognitive processing in older adults. Researchers gave Alpha BRAIN or a placebo to a group of 63 volunteers between ages 18 and 35 over six weeks. Researchers found volunteers in the Alpha BRAIN group had significant improvements in verbal recall, verbal memory, and executive functioning. This was the first published evidence proving Alpha BRAIN could work.

Alpha GPC is one of the largest ingredients in Alpha BRAIN, and multiple studies show alpha GPC can work to support powerful effects. A 2021 study, for example, found Alpha-Glycerylphosphorylcholine (alpha GPC) increased motivation in a group of healthy volunteers. Researchers found alpha GPC had a role in cholinergic function and monoaminergic transmission, which could help support dopamine and serotonin production – two neurotransmitters linked to motivation, reward processing, anxiety, and depression. Another study found alpha GPC was beneficial for certain physical and mental performance tasks.

L-tyrosine is another large ingredient in Alpha BRAIN. Many people take L-tyrosine daily for physical or cognitive performance. One 2018 study found oral tyrosine administration led to significant effects on the brain based on a neuro-imaging study. Researchers found L-tyrosine impacted cognitive performance in young adults, improved neurotransmitter transmission in the aging brain, and promoted overall cognitive health in various ways.

Many take L-theanine, another major ingredient in Alpha BRAIN, daily to support all cognition. A 2019 study published in Nutrients found L-theanine could help with stress-related symptoms and cognitive function in healthy adults. Many people take caffeine and L-theanine together for daily health and wellness. Although Alpha BRAIN does not contain caffeine, some take it daily with coffee or tea to support overall cognition.

Cat’s claw extract, or Uncaria tomentosa bark extract, is one of the largest ingredients in Alpha BRAIN, delivering 350mg per serving. According to Mount Sinai, cat’s claw has a long history of use in traditional medicine in South America, and modern studies show it can support cardiovascular health, immunity, muscle function, joint pain, and more. Some studies suggest cat’s claw extract supports physical and mental performance vita its anti-inflammatory effects.

Overall, Alpha BRAIN contains a blend of science-backed ingredients linked to health and wellness. And, it’s one of the few supplements in the nootropic space with a clinical trial published in a peer-reviewed medical journal. Although it may not supercharge cognition immediately, Alpha BRAIN has been shown to support memory, focus, motivation, and more with a science-backed formula.

Alpha BRAIN Supplement Facts Label

Onnit discloses all ingredients in the supplement upfront. Although Onnit uses three proprietary formulas (including a Flow Blend, Focus Blend, and Fuel Blend), the company lists all ingredients in the formula.

Here’s what you get in each two capsule serving (15 to 45 servings per container) of Alpha BRAIN:

  • 650mg of Onnit Flow Blend with L-tyrosine, L-theanine, oat straw extract, and phosphatidylserine
  • 350mg of cat’s claw bark extract
  • 240mg of Onnit Focus Blend with L-alpha glycerylphosphorylcholine (alpha GPC), Bacopa monnieri extract, and toothed clubmoss extract (standardized to contain 1% Huperzine A)
  • 60mg of Onnit Fuel Blend with L-leucine and pterostilbene
  • 10mg of vitamin B6 (as pyridoxine HCl) (588% DV)

Other (inactive) ingredients, including maltodextrin, vegetarian capsule (made from hydroxypropyl methylcellulose), and rice hull concentrate

Alpha BRAIN Reviews: What Do Customers Say?

Alpha BRAIN has strong reviews from customers online, with many taking the supplement daily for its targeted effects. We also appreciate Onnit’s commitment to transparency: unlike many supplement companies, Onnit leaves negative reviews on its official website instead of deleting them.

Overall, Onnit’s Alpha BRAIN has an average rating of 3.6 stars out of 5, with most customers either giving it a perfect 5-star rating or a disappointing 1-star rating. For many, Alpha BRAIN either works or does not work.

Here are some of the reviews shared by Alpha BRAIN users through the official website and other online sources:

Multiple customers report a significant improvement in their ability to focus after taking Alpha BRAIN, claiming they’re able to concentrate on tasks more efficiently.

Some customers have experienced a noticeable improvement in memory after taking Alpha BRAIN, and they find they’re able to recall certain information more easily.

Many customers claim Alpha BRAIN delivered noticeable benefits within as little as 15 minutes, although most claim it took 30 to 60 minutes to feel the effects of the formula.

Many like Alpha BRAIN as part of a daily habit for better cognition. It won’t immediately supercharge your brain in minutes like caffeine, but it can deliver steady, consistent energy to help you enter and maintain a state of flow.

Some use Alpha BRAIN daily for productivity and energy, while others take Alpha BRAIN before specific events – like tests, athletic events, or presentations.

Although Alpha BRAIN is popular as a cognitive supplement and nootropic, some also use it for physical activity, sports performance, the gym, and similar tasks. Alpha BRAIN can enhance focus and put you in a state of flow in a variety of situations.

Generally, the people leaving 1-star reviews found the supplement did not work as advertised for them. Some didn’t experience an immediate surge of energy, while others felt no difference whatsoever.

Overall, most Alpha BRAIN customers agree the supplement works as advertised to deliver powerful results, boosting cognition and supporting overall mental energy in multiple ways. Although some didn’t experience the effects of Alpha BRAIN, most agree the supplement offers good value.

Alpha BRAIN Pricing

Alpha BRAIN is available in 30 capsule (15 serving) or 90 capsule (45 serving) options. You can also subscribe to an Alpha BRAIN autoship program to save money.

Here’s how pricing works when ordering Alpha BRAIN online today:

Standard Bottle (30 Capsules / 15 Servings / 15 Day Supply)

  • 1 Bottle – One-Time Purchase: $34.95
  • 1 Bottle – Subscribe & Save: $29.71 (15% Off)
  • 2 Bottles: $52.44 ($26.22 per bottle) + free bonus gift (The Facts of Life with Joe Rogan book)
  • 3 Bottles: $73.41 ($24.47 per bottle) + free bonus gift (The Facts of Life with Joe Rogan book)

Large Bottle (90 Capsules / 45 Servings / 45 Day Supply)

  • 1 Bottle – One-Time Purchase: $79.95
  • 1 Bottle – Subscribe & Save: $67.96 (15% Off)

Onnit provides free shipping on orders over $150.

Alpha BRAIN Pricing

About Onnit

Onnit is a health and wellness brand offering a range of supplements. The company was founded with the goal of empowering as many individuals as possible for physical, mental, and spiritual wellbeing. To achieve that goal, Onnit offers people the tools they need to reach an optimal state.

Onnit summarizes its mission in three words: total human optimization (THO). The company was founded by Aubrey Marcus and is based in Austin, Texas.

In addition to Alpha BRAIN, popular Onnit supplements include Total Human, New MOOD, and Shroom TECH. Many of the company’s products have certifications from the Rainforest Alliance and UTZ, and Onnit continually tests products for purity and banned substances.

Onnit also makes unconventional training tools and fitness equipment. Plus, Onnit operates a gym in the Austin, Texas area.

You can contact Onnit and the Alpha BRAIN customer service team via the following:

Final Word

Onnit’s Alpha BRAIN continues to be one of the world’s most popular nootropic supplements.

With over one million bottles sold to date, Alpha BRAIN has been shown to deliver powerful effects on memory, cognition, focus, and motivation, using natural ingredients to put you in a state of flow.

To learn more about Alpha BRAIN or to buy the supplement online today, visit the official website.

Also Read: Mind Lab Pro Reviews (Updated)

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The links contained in this product review may result in a small commission if you opt to purchase the product recommended at no additional cost to you. This goes towards supporting our research and editorial team. Please know we only recommend high-quality products.


Please understand that any advice or guidelines revealed here are not even remotely substitutes for sound medical or financial advice from a licensed healthcare provider or certified financial advisor. Make sure to consult with a professional physician or financial consultant before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary and are not guaranteed as the statements regarding these products have not been evaluated by the Food and Drug Administration or Health Canada. The efficacy of these products has not been confirmed by FDA, or Health Canada approved research. These products are not intended to diagnose, treat, cure or prevent any disease and do not provide any kind of get-rich money scheme. Reviewer is not responsible for pricing inaccuracies. Check product sales page for final prices.

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