Advanced BioNutritionals Pure Sleep Reviews – Should You Buy?

Advanced Bionutritionals has launched a new sleep aid supplement called Pure Sleep.

Featuring a blend of natural ingredients, Pure Sleep aims to support a restful sleep without side effects or grogginess. Each bottle is priced at $39.95 as part of a 2023 sale.

Find out how Pure Sleep works and what the supplement does today in our review.

What is Pure Sleep?

Pure Sleep is a nutritional supplement from Advanced Bionutritionals. The company manufactures the formula in the United States in an FDA-registered, GMP-certified facility.

Priced at $39.95 per bottle, Pure Sleep uses a blend of natural ingredients to help you fall asleep, get a more restful sleep, and wake up feeling refreshed.

Pure Sleep was created by Dr. Janet Zand. Dr. Zand recommends the supplement to anyone who needs help falling asleep, calming their brain, or staying asleep all night long. The formula contains a mixture of herbs and plant extracts sourced from traditional Chinese medicine. These ingredients are backed by centuries of use, and Dr. Zand selected the ingredients specifically for sleep and relaxation.

All Pure Sleep purchases come with a 90 day moneyback guarantee. You can try the supplement for 90 days to see if you like it, then decide whether or not to keep it.

Pure Sleep Benefits

Some of the advertised benefits of Pure Sleep include:

  • 18 natural ingredients to help you fall asleep and stay asleep
  • Correct imbalances in your mind and body linked to sleep disturbances
  • Calm and soothe while supporting natural body rhythms
  • Shut down mental chatter and help support stress response
  • Ease tossing and turning, boost memory and mood, and wake up feeling refreshed
  • Promote balanced levels of GABA and other neurotransmitters linked to rest and relaxation

How Does Pure Sleep Work?

If you’re like many people, then your busy brain keeps you awake at night. Pure Sleep uses natural ingredients to help you calm your brain, helping you fall asleep in minutes and stay asleep.

Dr. Zand developed Pure Sleep to target the root cause of sleepless nights: GABA imbalances in your brain. GABA is a neurotransmitter linked to calmness and relaxation. As Dr. Zand explains, GABA “acts like the ‘brakes’ of your brain” by putting a stop to racing thoughts. Instead of feeling anxious and stressed all night, you can stay relaxed with GABA.

However, your brain produces less GABA as you age. That’s why many people struggle with a restful sleep as they get older.

Many of the ingredients in Pure Sleep are designed to promote balanced GABA levels without side effects, allowing you to enjoy a deep, restful, and rejuvenating sleep.

Other ingredients work in different ways. Some promote healthy blood flow and clearer breathing, for example. When you can breathe more easily, your body can easily pass oxygen throughout your body, making it easier to relax. You can calm yourself physically and mentally, making it easier to stay asleep.

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Other ingredients have complementary effects. They work together to promote a healthy sleep.

Pure Sleep Ingredients

Some of the ingredients in Pure Sleep trace their roots to traditional Chinese medicine. Others are backed by centuries of use in wellness remedies, relaxation formulas, and other supplements.

Some sleep aid supplements contain one or two ingredients for a restful night of sleep. Other supplements contain dozens. With Pure Sleep, you get 17 nutrients to help you fall asleep and stay asleep.

Here are all of the active ingredients in Pure Sleep and how they work, according to Dr. Zand and the Advanced Bionutritionals formulation team:

Honokiol: Honokiol is a type of magnolia bark extract. According to Dr. Zand, the unique ingredient “raises GABA levels in the brain” while shutting down the chatter that keeps you awake. Traditional Chinese medicine practitioners have been using this bark extract for 2,000 years for anxiety, stress relief, and depression. Today, growing research backs up its effects as a sleep inducing ingredient. Some studies show honokiol stimulates GABA receptors in the brain to promote non-REM sleep. Other studies showed honokiol was as effective as conventional remedies for reducing stress and anxiety.

Lemon Balm: Found in many sleep aid supplements for its effects on relaxation, lemon balm has a long history of use in traditional remedies. The ancient Greeks, according to Dr. Zand, used the herb for medicinal purposes to soothe agitation, relieve anxiety, and ease pain. In one study, it reduced symptoms of anxiety by 72% within just 15 days. Researchers believe lemon balm works because it contains receptors in the brain that promote relaxation and positive feelings. It also improves mental clarity, putting you in a state of calm focus for maximum productivity.

Passion Flower: Another popular sleep aid supplement ingredient, passion flower is known as a mild relaxant. According to Dr. Zand and the Advanced Bionutritionals team, it also “helps increase GABA levels” while relieving stress and anxiety – similar to how honokiol works. However, passion flower has unique benefits compared to honokiol. It relieves muscle aches and other discomfort, for example, and soothes your aches and pains. It also has complementary effects with other calming herbs, including lemon balm and honokiol.

Melatonin: Pure Sleep contains a small dose (0.5mg) of melatonin. Advanced Bionutritionals deliberately added the small dose to promote sleep without grogginess. Many sleep aid supplements contain 2mg to 10mg of melatonin per serving, which is considered a strong dose. A healthy adult produces around 0.3mg of melatonin per day. When you take larger doses of melatonin, you could disrupt your body’s natural production of the hormone. With 0.5mg of melatonin per serving, Pure Sleep aims to promote restfulness without interrupting sleep.

Vitamin B3: Pure Sleep contains vitamin B3, or niacinamide. According to Dr. Zand, melatonin works particularly well when combined with vitamin B3, which is why the two nutrients are often found together in sleep and relaxation aids.

L-Theanine: A natural amino acid found in green tea and certain plants, L-theanine is known for its relaxing properties. Many people drink green tea and L-theanine daily to promote relaxation and calm motivation. Studies show L-theanine can calm the mind and improve attention and focus – all within as little as 45 minutes.

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L-Tryptophan: Tryptophan is the amino acid in turkey meat that makes you feel sleepy after Thanksgiving dinner. Many sleep aid supplements contain this same amino acid to help you relax and relax. Studies show tryptophan works by raising levels of serotonin, one of your brain’s most important natural chemicals. Serotonin sends a signal to your brain that you’re sleepy, helping you rest and relax – and stay asleep. It’s also one of your brain’s “feel good” neurotransmitters, and normal serotonin levels are linked with a good mood and reduced symptoms of depression and anxiety. For all of these reasons and more, tryptophan is one of the most important amino acids you can take for rest and relaxation.

Magnesium: Pure Sleep contains magnesium, an important nutrient considered an “anti-stress” mineral by Dr. Zand and the Advanced Bionutritionals team. People who are deficient in magnesium may have impaired nerve and muscle function. Magnesium helps to gently relax your muscles, making it easier to physically calm your body at night – and fall asleep. One 2012 study analyzed the effects of magnesium on a group of elderly patients with insomnia. Nearly 50% of older adults have insomnia, and researchers wanted to see if magnesium could help. Researchers found magnesium supplementation improved sleep efficiency, sleep time, sleep onset latency, and overall insomnia severity index (ISI) scores.

Calcium: Calcium is known for supporting bone health. However, calcium is also critical for a good sleep. In fact, calcium is the reason people traditionally drank a glass of milk before bed to help fall asleep. Today, we know calcium has natural relaxant properties that make it ideal for use as a sleep aid It can help with muscle tension and sleeplessness, making it easier to fall asleep and stay asleep.

White Peony Root: White peony root is known for its ability to support liver health. It “helps your liver store nighttime blood,” according to Dr. Zand. Your liver naturally stores more blood at night to help you fall asleep. White peony root promotes normal liver blood storage at night while also helping to relieve anxiety, discomfort, and more. White peony extract’s ability to promote sleep is so renowned, in fact, that an inventor once patented the supplement for “improving the duration and quality of sleep,” receiving a patent from the United States Patent Office in 2005.

Polygonum Vine Stem: Polygonum vine stem is the second listed ingredient in the Pure Sleep proprietary formula, which means there’s significantly more of this ingredient than many others in the supplement. Polygonum vine stem is used in Chinese medicine to help calm the heart and protect the brain. It can also boost serotonin levels and promote healthy mood balance – similar to how tryptophan works. Although not as extensively studied as other ingredients in Pure Sleep, one recent study found polygonum vine stem extract could promote “sleep homeostasis” by targeting the activity of specific enzymes and chemicals within the body, helping you relax.

Sweetflag Rhizome Extract: Sweetflag rhizome extract is another Chinese herb used to clarify the heart and lungs. In Pure Sleep, this same ingredient “clears the head and promotes deep restful breathing,” according to Dr. Zand. When you breathe more clearly, it can help relax your body, promoting a deeper and more restful sleep.

Red Sage Root: Red sage root is a popular Chinese remedy backed by thousands of years of use. It’s used to promote healthy blood circulation, support healthy inflammation, and relax the mind. If your body is inflamed or struggling with circulation, then it can be difficult to relax and fall asleep. Red sage root works to complement the other ingredients in Pure Sleep’s formula to deliver active effects.

Sacred Lotus Seed Sprout: Sacred lotus seed sprout is an all-around health tonic to energize the heart, liver, spleen, kidneys, and intestines. Used as a general remedy for health and wellness, sacred lotus seed sprout could help you relax, fall asleep, and get a more restful sleep.

Chinese Date Seed: Chinese date seed can enhance muscle strength and promote healthy cardiovascular function, according to Advanced Bionutritionals. By taking Chinese date seed daily, you can support blood flow, muscle relaxation, and more, making it easy to physically relax and fall asleep.

Mimosa Tree Bark: Mimosa tree bark works in a similar way to arborvitae and sweetflag rhizome, two other active ingredients in Pure Sleep. It helps calm the heart, promoting healthy inflammation and circulation. However, mimosa tree bark can also help balance the liver, relieve digestive woes, and support nervous system health. If your body is struggling with digestion, then it can be difficult to fall asleep. Mimosa tree bark could help.

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Pure Sleep Supplement Facts Label

Most of Pure Sleep’s ingredients are found within a 280mg proprietary formula. However, Advanced Bionutritionals discloses all ingredients and many dosages upfront, helping you compare the supplement to other sleep aid formulas sold online today.

Here are all of the ingredients in each serving (two capsules) of Pure Sleep:

280mg of the EcoNugenics Proprietary Sleep Blend with HonoPure (98% honokiol from magnolia bark extract), polygonum vine stem extract, white peony root extract, Chinese arborvitae seed extract, Chinese date seed extract, mimosa tree bark extract, red sage root extract, sacred lotus seed sprout extract, and sweetflag rhizome extract

  • 110mg of lemon balm extract
  • 110mg of passionflower
  • 100mg of L-tryptophan
  • 50mg of L-theanine
  • 0.5mg of melatonin

Other (inactive) ingredients, including vegetable cellulose and water (to create the vegetable capsule) along with tapioca flour, stearic acid, silicon dioxide, and vegetable cellulose

Pure Sleep Supplement Facts

Pure Sleep Reviews: What Do Customers Say?

Pure Sleep has average to strong reviews online from most customers. Most customers found Pure Sleep worked as advertised to support a healthy sleep. However, some customers find it wasn’t very effective. It works on some people, but not others – which is why we appreciate the 90 day money back guarantee.

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Here are some of the reviews shared by verified purchasers on the official Pure Sleep website:

Overall, Pure Sleep has an average rating of 3.5 stars out of 5 with 275+ customer reviews. 68% of reviewers recommend the supplement.

One customer described Pure Sleep as a “great sleep aid” because it helped him fall asleep more quickly.

Some customers use Pure Sleep after trying other sleep aids, relaxation methods, and strategies. One customer claims he tried “a number of sleep aids” before he started to regularly use Pure Sleep. He likes Pure Sleep because it’s natural and does not leave him groggy in the morning.

Some people take one capsule of Pure Sleep per night, while others take two. Depending on your sensitivity to the ingredients, you might want to take one serving (two capsules) or half a serving (one capsule).

Some customers use Pure Sleep regularly for years with continued effectiveness. One customer claims he has been taking Pure Sleep “for a few years” to enjoy great, peaceful sleeps.

Another customer claims he has “no trouble falling asleep” thanks to Pure Sleep.

Some customers started to take Pure Sleep because they found themselves tossing and turning all night long. With Pure Sleep, they can enjoy a relaxing, rejuvenating, toss-free sleep.

Overall, most customers agree Pure Sleep works as advertised to promote a restful sleep. However, the supplement does not work on everyone, and some people take advantage of Advanced Bionutritionals’ 90 day moneyback guarantee because they’re unhappy with the results.

Pure Sleep Pricing

Pure Sleep Pricing

Pure Sleep costs $39.95 per bottle as part of a 2023 promotion. You can pay even less by ordering multiple bottles of Pure Sleep.

Here’s how pricing works when ordering Pure Sleep online today:

  • 1 Bottle: $39.95
  • 3 Bottles: $107.85 ($35.95 Per Bottle)
  • 6 Bottles: $199.50 ($33.25 Per Bottle)

Each bottle contains 60 capsules, or 30 servings. You take two capsules nightly to support a healthy sleep.

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Pure Sleep Refund Policy

Advanced Bionutritionals offers a 90 day moneyback guarantee on most supplements, including Pure Sleep. If you’re unhappy with Pure Sleep for any reason, then you can request a complete refund within 90 days. You only pay for return shipping.

About Advanced Bionutritionals

Advanced Bionutritionals is an American supplement company with several medical doctors, naturopathic doctors, and other certified specialists on its advisory board. Pure Sleep was specifically created by Dr. Janet Zand, OMD, L Ac.

To contact Advanced Bionutritionals and the Pure Sleep customer service team, use the following:

  • Phone: 800-791-3395
  • Email: [email protected]
  • Mailing Address: P.O. Box 8051, Norcross, GA 30091-8051
  • Company Headquarters: 5305 Oakbrook Parkway, Norcross, GA 30093

Advanced Bionutritionals was founded with the goal of offering advanced nutraceuticals formulated by doctors. Today, the company and its team of doctors offer many popular formulas, including Advanced Mitochondrial Formula, Zinc Acetate, Advanced Liver Support, and CircO2, among others.

Final Word

Pure Sleep is a nutritional supplement featuring a blend of Chinese herbs and plant extracts, vitamins, minerals, and amino acids to help you fall asleep.

By taking one or two capsules of Pure Sleep in the evening, you can promote your body’s natural relaxation processes, making it easier to fall asleep, stay asleep, and wake up refreshed without grogginess.

To learn more about Pure Sleep and how the supplement works, or to buy the sleep aid formula online today, visit the official website.

Also Read: Advanced BioNutritionals Advanced Amino Formula Review

Affiliate Disclosure:

The links contained in this product review may result in a small commission if you opt to purchase the product recommended at no additional cost to you. This goes towards supporting our research and editorial team. Please know we only recommend high-quality products.


Please understand that any advice or guidelines revealed here are not even remotely substitutes for sound medical or financial advice from a licensed healthcare provider or certified financial advisor. Make sure to consult with a professional physician or financial consultant before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary and are not guaranteed as the statements regarding these products have not been evaluated by the Food and Drug Administration or Health Canada. The efficacy of these products has not been confirmed by FDA, or Health Canada approved research. These products are not intended to diagnose, treat, cure or prevent any disease and do not provide any kind of get-rich money scheme. Reviewer is not responsible for pricing inaccuracies. Check product sales page for final prices.

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