CircO2 Reviews – Should You Buy Advanced BioNutritionals NO2 Booster Formula?

CircO2 is a nitric oxide boosting formula from Advanced Bionutritionals.

Using a blend of natural ingredients, CircO2 aims to support healthy circulation by promoting nitric oxide levels using quick-dissolving tablets and natural ingredients.

Does CircO2 really work? How does CircO2 promote nitric oxide production and circulation? Keep reading to find out how CircO2 works and what the supplement does today in our review.

What is CircO2?

CircO2 is a blood circulation supplement available exclusively online.

According to Advanced Bionutritionals, the Norcross, Georgia-based company behind the supplement, CircO2 is “proven to boost nitric oxide 200% higher than arginine in just minutes.”

Each quick-dissolving tablet of CircO2 contains a blend of natural ingredients to promote nitric oxide production. Nitric oxide, or NO, is a molecule your body naturally produces to widen blood vessels and promote circulation. Higher levels of NO are associated with better blood flow and reduced blood pressure.

CircO2 is available through the Advanced Bionutritionals online store, where it’s priced at around $49.95 per box. All purchases come with a 90 day moneyback guarantee.

CircO2 Benefits

According to Advanced Bionutritionals, CircO2 can promote a range of benefits within 20 minutes, including:

  • Boost energy
  • Sharpen memory
  • Increase stamina
  • Enhance sexual performance
  • Help support healthy blood pressure

How Does CircO2 Work?

CircO2 works by targeting nitric oxide (NO), a molecule in your body linked to blood flow. Your body produces NO on its own. However, taking certain foods or supplements can increase your body’ s natural production of NO.

Nitric oxide is critical for overall health and wellness. It helps promote healthy blood flow by widening and relaxing your blood vessels. It makes it easier for blood to flow throughout your body, which can help with blood pressure, energy, relaxation, heart rate, and sexual health, among other benefits.

CircO2 comes in the form of a dissolvable tablet. You let the tablet dissolve on your tongue, and your body absorbs the active ingredients immediately through the sensitive skin around your mouth. You swallow the remaining tablet, allowing the ingredients to continue working throughout your body.

Visit the official CircO2 website to learn more >>>

What Does Nitric Oxide Do?

Advanced Bionutritionals describes nitric oxide as a “miracle molecule” for its ability to promote a healthy heart, sharp memory, and nonstop energy.

When your body produces ample nitric oxide, you tend to have lower blood pressure, better blood flow, improved energy, and sharper physical and cognitive performance, among other benefits.

Here are some of the effects nitric oxide has in your body, according to Advanced Bionutritionals:

  • Tells your arteries to relax, helping them open wider and causing blood to flow freely to promote healthy blood pressure and reduce cardiovascular health risks
  • Fuels your body with long-lasting, sustainable energy for better stamina and performance
  • Wakes up your brain to send and receive signals more quickly
  • Boosts the formation of bone and slows bone breakdown
  • Signals your immune system to kill bacteria, viruses, and other harmful invaders
  • Promotes mood and overall sense of wellbeing, supports healthy muscle and joint recovery, and enhances blood flow to sexual organs for better performance, among other benefits
  • Many of these benefits are linked to blood flow. Nitric oxide promotes better blood flow, and better blood flow is associated with overall health and wellness throughout your body.

Nitric Oxide Production Drops with Age

Your body produces nitric oxide on its own. So why do you need a nitric oxide supplement?

Unfortunately, nitric oxide production decreases with age.

Your body produces the maximum amount of nitric oxide in your 20s. By the time you’re in your 40s, however, they’re at just 50% of their previous levels. In your 60s, your body is producing just 15% of the nitric oxide it produced at its peak. These lower nitric oxide levels can contribute to higher blood pressure and lower energy – symptoms many associate with aging.

Falling nitric oxide production is linked to your endothelium, which is the lining inside all of your blood vessels. Your endothelium is crucial for delivering oxygen and nutrients throughout your body. It also produces nitric oxide, helping to keep blood vessels flexible and wide to promote good blood flow.

When you’re young, your endothelium is healthy and active. It provides a steady current of nitric oxide to push oxygen and nutrients anywhere in your body they need to go.

When you get older, however, your endothelium doesn’t produce as much nitric oxide. You might feel increased symptoms of aging. Your energy could drop. Your blood pressure could rise. CircO2 works by counteracting this effect using natural ingredients, promoting nitric oxide production at any age.

Try CircO2 today and see the difference!

CircO2 Ingredients

CircO2 contains a blend of natural ingredients to promote your body’s natural nitric oxide production.

Many of the ingredients in CircO2 work by giving your body the building blocks of nitric oxide. Beetroot powder, one of the active ingredients in CircO2, is rich with nitrates, for example, that are linked to nitric oxide production. By taking the nitrates in CircO2 daily, you can boost your body’s natural NO production.

Here are all of the active ingredients in CircO2 and how they work to promote NO production and circulation:

L-Citrulline: One of the most important ingredients in CircO2 is L-citrulline. The amino acid is found in many preworkout supplements and natural energy boosters for its ability to widen blood vessels and promote healthy blood flow. Today, CircO2 uses the same amino acid to increase nitric oxide throughout your body. According to Advanced Bionutritionals, L-citrulline is backed by “a growing amount of research” linking it to healthy blood pressure levels. Other studies have linked L-citrulline to better bedroom performance. Some athletes take L-citrulline for energy, stamina, and brainpower. For all of these reasons and more, L-citrulline is one of the most important ingredients in the CircO2 formula.

Beetroot Powder: CircO2 contains beetroot powder to help you think clearly and support physical and cognitive performance. According to Advanced Bionutritionals, the beetroot powder in CircO2 is “able to open up your blood vessels and increase blood flow,” boosting energy and supporting overall cardiovascular health. And, instead of eating dozens of beets per day, you can get a single serving of CircO2’s dissolvable tablet.

Hawthorn Berry: Hawthorn berry is rich with natural antioxidants like vitamin C. The small, red berry has a long history of use in traditional medicine. Today, we know it works as a traditional remedy because it’s rich with vitamin C, one of nature’s best antioxidants. Like other antioxidants, vitamin C works throughout your body to promote healthy inflammation. It neutralizes the effects of frere radicals and helps support inflammation, which is linked with disease and illness. Hawthorn also has an additional effect: according to Advanced Bionutritionals, the hawthorn berry in the formula helps your body absorb more L-citrulline and beetroot powder than it normally would.

Vitamin B12: CircO2 contains vitamin B12, a popular vitamin for energy and performance. Many people – especially vegans and vegetarians – are deficient in vitamin B12 because there are few plant-based sources of the vitamin. Each serving of CircO2 contains 1,000mcg of vitamin B12 to increase nitric oxide levels and support brain, nerve, and muscle function.

Vitamin C: CircO2 contains vitamin C, a powerful antioxidant linked to nitric oxide levels. It stimulates the activity of an enzyme linked to nitric oxide, helping to increase overall nitric oxide. Vitamin C is also naturally present in hawthorn berry and certain other ingredients in CircO2, and it contributes to the active effects of the supplement in multiple ways.

Magnesium: About 80% of American adults are deficient in magnesium, which is a problem because magnesium is critical for muscle function and blood flow. Your body needs magnesium to promote healthy heart rhythm. Calcium also keeps calcium from building up in your brain, heart, and joints – all of which are linked to health risks. For all of these reasons and more, many people take a magnesium supplement daily for health and wellness.

Overall, the unique combination of ingredients in CircO2 can purportedly boost nitric oxide “200% higher than arginine” alone in just minutes. Sure, you could take arginine for blood flow. However, CircO2 combines citrulline – which works similar to arginine – with other natural ingredients to promote healty blood flow and NO levels.

CircO2 Is On Sale Now For A Limited Time!

Scientific Evidence for CircO2

Most supplements aren’t backed by specific scientific evidence. Clinical trials are expensive, and supplement companies may not want to invest in them. However, CircO2 is backed by clinical trials on the specific blend of ingredients.

Here’s how one study worked using a supplement with the same ingredients and combinations in CircO2:

Researchers tested a formula that has the same ingredients in the same combinations as you get in CircO2, including the same quick-dissolving delivery system.

Researchers gathered a group of people with high blood pressure, then measured blood pressure before and after taking the supplement.

20 minutes after taking the supplement, researchers found participant’s systolic blood pressure had dropped by 4 points and diastolic blood pressure had dropped by 5 points.

After 60 minutes, researchers found these numbers had fallen even further. According to Advanced Bionutritionals, “even their blood vessels had gotten healthier” after 60 minutes.

The individual ingredients in CircO2 are also backed by scientific evidence. A 2019 review analyzed the effects of citrulline on blood pressure, for example, and found a significant connection between the two. Researchers found supplementation of 3,000mg to 9,000mg of L-citrulline per day was associated with an average drop of 4.10 mm Hg for diastolic and 2.08 mm Hg for diastolic blood pressure.

Some people take beetroot juice or beetroot extract daily for blood pressure. A 2018 study published in Biomolecules found dietary nitrate could help control arterial blood pressure in adults with pre-hypertension. Based on the results of the study, researchers concluded beetroot could be used to complement diet and exercise changes to control high blood pressure.

Some studies suggest vitamin B12 deficiency is a risk factor for cardiovascular disease in vegetarians. A 2015 study published in the American Journal of Preventive Medicine, for example, found a connection between vitamin B12 deficiency and high blood pressure, high cholesterol, and other risk factors for heart disease. Because of this connection, people deficient in vitamin B12 – including many vegans and vegetarians – may consider taking a vitamin B12 supplement.

Overall, CircO2 contains a blend of science-backed ingredients, and the supplement as a whole has been studied to verify it works. The formula was also created by medical professionals. All of this evidence gives CircO2 an edge over competing NO supplements.

Place your order today before stock runs out!

What to Expect After Taking CircO2

Advanced Bionutritionals primarily markets CircO2 to older adults who wan tot boost energy and support healthy blood flow.

Here are some of the results adults of all ages could experience after taking CircO2, according to the official website:

Get back your youthful energy. NO production naturally drops with age, which could make you feel old and lethargic. CircO2 works by helping you regain the energy you thought was lost forever. You can play with your grandchildren, work in your garden, play sports, and do all of the activities you used to enjoy.

Enjoy greater endurance and stamina. Some people walk further without getting winded after taking CircO2. Others easily get all of their shopping done without worrying about losing energy.

Some take control of their blood pressure levels naturally with CircO2. A healthy diet and exercise routine can lower blood pressure. However, the natural ingredients in CircO2 can complement a healthy diet and exercise routine, supporting overall cardiovascular health.

Boost memory. Some people can recall names, grocery lists, and items around the house more easily after taking CircO2, according to Advanced Bionutritionals. When you have better blood flow, you enjoy sharper cognition and better memory, among other effects.

Enjoy clear, healthy arteries with strong circulation. NO is crucial for healthy circulation. Your body needs NO to circulate blood throughout your body. CircO2 can promote healthy circulation and keep arteries clear and healthy, according to the manufacturer.

Support bone health and bone strength. Many of the natural ingredients in CircO2 also promote your body’s bone building process. Your body needs these same ingredients to stay healthy and strong.

Boost sexual performance for stronger erections, better arousal, and greater sexual enjoyment in the bedroom.

Stay more active easily and boost recovery. As you get older, a workout can leave you feeling tired for days. CircO2 can enhance recovery.

Support healthy joints and mobility. Doe joint health prevent you from being active? CircO2 may be able to help, giving your body a blend of ingredients to keep joints flexible and mobile with age.

Lift mood and keep your spirits high. Some of the ingredients in CircO2 are associated with neurotransmitters and brain chemicals. Better blood flow to the brain can also promote a better mood. CircO2 works to lift your mood and keep your sprits high.

Supercharge your immune system to fight off viruses and bacteria.

Buy CircO2 Before it’s SOLD OUT

CircO2 Supplement Facts Label

Some of the active ingredients in CircO2 are found within a proprietary formula, while others are not. We know all of the ingredients in CircO2 and most of the dosages, helping you compare the supplement to other NO formulas, circulation supplements, and other health products sold online today.

CircO2 Supplement Facts

Here are all of the active ingredients in CircO2 and how they work:

  • 100mg of vitamin C (167% DV)
  • 1,000mcg of vitamin B12 (16,667% DV)
  • 420mg of a Proprietary Nitric Oxide Blend with beetroot powder, hawthorn berry extract, L-citrulline, and sodium nitrite

Other (inactive) ingredients, including mannitol, modified cellulose, xylitol, natural flavors, magnesium, vegetable stearate, stevia, silica, and natural carmine color

CircO2 Reviews: What Do Verified Customers Say?

Advanced Bionutritionals is known for offering honest reviews on its online store. The company does not seem to comb its reviews or silence verified purchasers. Instead, they disclose reviews and ratings upfront for maximum transparency.

Overall, CircO2 has a 3.8 star rating from the Advanced Bionutritionals online store with 1,180+ reviews. 74% of purchasers recommend the supplement. Most customers are satisfied with how CircO2 works and what the supplement does, although some seem to have not experienced the full effects of the formula.

Here are some of the reviews shared by verified purchasers:

One husband-and-wife couple takes CircO2 regularly for circulation and health. They’re 79 and 76 and they claim to have “noticed a definite increase” in energy levels after taking CircO2. They do not hesitate to recommend the supplement to friends and family members who also want an energy boost.

One customer claims CircO2 “helped to control my hypertension,” or high blood pressure. She already takes medication for her high blood pressure, and she found the supplement worked in tandem with her blood pressure medication to control her BP “to a relatively safe level.”

Another verified purchaser has taken CircO2 for over a year. She periodically stops taking the supplement and notices her blood pressure and heart rate increase during these times. She attributes her good cardiovascular health to CircO2.

CircO2 is popular among active individuals, and many people find they perform better athletically with higher nitric oxide levels. One positive CircO2 review comes from a 74-year old cyclist, for example, who has noticed improved performance since taking CircO2. Before taking the supplement, he noticed his performance continued to decrease with age.

Some people sleep better at night thanks to CircO2. They maintain a comfortable temperature, keep blood flowing throughout their body, and breathe better all night thanks to CircO2.

One reviewer described CircO2 as the “best nitric oxide supplement on the market”.

Another customer claims she “noticed within days that my circulation improved” after taking CircO2.

Some people notice fewer leg cramps and other symptoms in their extremities thanks to CircO2. One customer had leg cramps for “years” before trying CircO2. Now, she has reduced her cramps significantly thanks to the supplement.

Overall, CircO2 contains a blend of ingredients linked to energy, blood flow, nitric oxide production, and overall wellness. Most reviewers are happy with how CircO2 works and take it semi-regularly to promote overall health.

CircO2 Pricing

CircO2 Pricing

CircO2 costs $49.95 for a one month supply (30 tablets). You take one quick-dissolving tablet daily to promote blood flow and NO production.

Here’s how much you pay when ordering CircO2 online today through the official store:

  • 1 Box: $49.95
  • 3 Boxes: $134.85 ($44.95 Per Box)
  • 6 Boxes: $249 ($41.50 Per Box)

CircO2 Is On Sale Now For A Limited Time!

CircO2 Refund Policy

CircO2 has a 90 day moneyback guarantee, which is the same refund policy for most Advanced Bionutritionals supplements. You have 90 days to try CircO2, decide if you like it, and request a refund if dissatisfied for any reason.

About Advanced Bionutritionals

CircO2 was developed by a nutraceutical company named Advanced Bionutritionals. Based in Norcross, Georgia, that company manufactures CircO2 in the United States in an FDA-registered, GMP-certified facility. Advanced Bionutritionals also has an advisory team of medical doctors and other health professionals, including Dr. Janet Zand, OMD, L Ac, who formulated CircO2.

Contact Advanced Bionutritionals and the company’s customer service team using the following methods:

  • Phone: 800-791-3395
  • Email: [email protected]
  • Mailing Address: P.O. Box 8051, Norcross, GA 30091-8051
  • Company Headquarters: 5305 Oakbrook Parkway, Norcross, GA 30093

In addition to CircO2, other popular Advanced Bionutritionals supplements include Pure Sleep, Advanced Mitochondrial Formula, PerfectAmino, and Advanced Memory Formula, among others. The company’s supplements target liver health, bladder function, blood pressure, blood sugar, bone health, immunity, sleep, and more.

Advanced Bionutritionals manufactures supplements in GMP-certified, FDA-registered facilities in the United States. The company uses no artificial colors, artificial binders, artificial fillers, or artificial preservatives. Plus, they test all batches of ingredients using FTIR spectrometers for purity and potency.

Final Word

CircO2 is a nutritional supplement featuring a blend of citrulline, beetroot extract, and other natural ingredients to promote healthy blood flow.

By taking dissolvable CircO2 tablets daily, you can give your body the building blocks it needs to produce nitric oxide, a molecule linked to healthy blood flow. Your body produces nitric oxide (NO) naturally, although production declines with age.

To learn more about CircO2 and how it works or to buy the supplement online today, visit the official website.

Also Read: Advanced Blood Pressure Formula (Advanced BioNutritionals)

Affiliate Disclosure:

The links contained in this product review may result in a small commission if you opt to purchase the product recommended at no additional cost to you. This goes towards supporting our research and editorial team. Please know we only recommend high-quality products.


Please understand that any advice or guidelines revealed here are not even remotely substitutes for sound medical or financial advice from a licensed healthcare provider or certified financial advisor. Make sure to consult with a professional physician or financial consultant before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary and are not guaranteed as the statements regarding these products have not been evaluated by the Food and Drug Administration or Health Canada. The efficacy of these products has not been confirmed by FDA, or Health Canada approved research. These products are not intended to diagnose, treat, cure or prevent any disease and do not provide any kind of get-rich money scheme. Reviewer is not responsible for pricing inaccuracies. Check product sales page for final prices.

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