Top 10 Best Immunity Boosters That Work: Most Effective Immune System Supplements

The human body is a fantastic machine that can heal when given the right tools. If you’ve ever been sick or had a nasty bug going around in your house, you know how important it is to maintain good health habits and eat well so that your immune system can fight off germs effectively.

There is a constant battle against germs and bacteria in our bodies. This is natural and essential for optimum health. However, the immune system is challenged with too many germs and bacteria that have evolved to outwit the immune system. As a result, the immune system weakens and starts rejecting healthy cells and tissues, which can lead to diseases like cancer, infections, etc.

However, many people have chronic conditions such as autoimmune diseases or allergies that are hard to cure with a regular diet or lifestyle change. So, in that case, when health takes a turn for the worse, it’s essential to know how to boost our immune systems to prevent diseases.

One of the best ways to improve your overall health and immunity is by using immune boosters that naturally support optimal immune system functioning. And when you search for the best immune-boosting supplement online, it becomes daunting to find the right one.

In that case, this article is beneficial for you. Our research demonstrates that the following list of best immunity boosters is among the best on the market that contains all-natural ingredients with essential vitamins and minerals to support immune health.

We have curated this list after considering essential factors, such as price, honest advertised benefits, manufacturing process, and more.

But before we head to the list, it is essential to understand what is an immune-boosting supplement and how does it work?

By definition, an immune-boosting supplement is a supplement that helps support the body’s natural defense system. This can be accomplished through several different mechanisms. For example, some supplements can help reduce inflammation and improve the function of the immune system by increasing white blood cells or stimulating macrophages.

The Best Immunity Boosters for 2023

VitaPost Immune Support One of the best immune boosters that contain all essential nutrients to promote the immune system’s health.
Mushroom Defense Manage stress and immune function for healthy living.
VitaPost Immune Complex It contains a powerful blend of ingredients proven to maintain overall health.
Zenith Labs Nano C This liquid formula offers a maximum level of vitamin C with higher bioavailability.
Epishield Plus It enhances immune function and reduces the risk of respiratory function.
Advanced Bionutritionals Resistol The increased energy level and physical performance
Organixx 7M It contains a mushroom blend for a better immune system, brain function, digestion, and more.
BioShield MD Shields your body from various infections and viruses
VitaPost Turmeric & Ginger Enhance overall health, from immunity to joint health
Immuno Defense 4 X Support immunity and fight against free radical damage.

VitaPost Immune Support

VitaPost Immune Support

Ingredients Beta-Glucans, Quercetin, Green Tea, Vitamin E, Vitamin C, Arabinogalactan, and Olive leaf Extract
  • Generate healthy immune cells to ensure the body works properly to fight against infectious diseases and certain infections
  • Reduce the risk of chronic inflammation and build a robust immune system
  • Raises the level of white blood cells to improve certain health conditions
  • Prevents nutrient deficiency such as iron and so on
Price $13.95

VitaPost Immune Support is a natural formula that helps boost the immune system. It contains vitamins, minerals, and other beneficial ingredients that help support healthy immune function and fight off infection and inflammation.

This supplement is safe to use and does not have any side effects. Thus, if you are looking for a natural supplement that can support your immune system and overall health, Vitapost Supplement is worth considering.

It helps restore cell balance, leading to good health and well-being. In addition, this formula also supports overall health and well-being by providing vitamins, minerals, antioxidants, and other nutrients that help healthy immune function.

Mushroom Defense

Mushroom Defense

Ingredients Maitake, Turkey Tail, Chaga, Royal Sun Agaricus, White Button, Cordyceps Sinensis, Reishi, Shiitake, Lion’s Mane, and Black Fungus.
  • Support a healthy immune response for boosting immunity
  • Aid in managing stress and support brain function
  • Ensure a healthy gut and enhance overall health
  • It works as a powerful antioxidant and is known for its antiviral effects.
Price $59.99.

As mushrooms contain polysaccharides that can block toxins from attacking cells in the body. These polysaccharides work together with other immune system agents like white blood cells to protect the body against pathogens.

By protecting our bodies against toxins and pathogens, mushrooms help to lower our risk for numerous diseases. Their protective effects on the cardiovascular system may help keep us healthy throughout life!

Hence, there is no doubt why the manufacturer of Mushroom Defense claims that this is one of the herbal supplements that contain superfoods that have immune-enhancing properties. However, this supplement is a perfect addition to a healthy diet for living a healthy lifestyle.

VitaPost Immune Complex

VitaPost Immune Complex

Ingredients Turmeric, Vitamin C, Garlic, Vitamin E, Vitamin B6, Zinc, L-Glutamine, echinacea, probiotics, and Elderberry fruit extract
  • It contains powerful anti-inflammatory ingredients to boost immune system health.
  • Aid in maintaining a healthy lifestyle by controlling high blood pressure
  • Reduces the increased risk of chronic disease
  • Help to prevent chronic stress.
Price $17.95

VitaPost Immune Complex is a dietary supplement designed to help improve your overall health. It contains various ingredients that have been proven beneficial for immune system function, such as vitamin C, elderberry, and more. These ingredients boost the body’s natural defenses against infection and promote better health.

There are many potential benefits to taking VitaPost Immune Complex. Some believe it can help reduce the risk of infections by helping strengthen the body’s defenses against disease. Others think it can help boost the immune system so that you’re better equipped to fight off illness head-on. And still, others believe that it can reduce inflammation in our bodies, which may lead to improvements in various health conditions such as respiratory infections, the common cold, and more.

Zenith Labs Nano C

Zenith Labs Nano C

Ingredients Only Vitamin C
  • Fortifies the body’s immune system
  • It helps in promoting the production of antibodies
  • Help in faster recovery from viruses and bacterial infectious diseases
  • Act as a perfect defense for cold and flu season.
Price $49.

We all know that vitamin C plays a unique role in supporting immune response, so Dr. Ryan Shelton has added only this nutrient to Zenith Labs Nano C.

Out of many vitamin C supplements, Nano C is like no other. The makers have used cutting-edge nanotechnology that enhances the absorption of the formula.

Its nano form ensures that it contains vitamin C particles 1,000 times smaller than ordinary Vitamin C. This not only helps your body absorb more of the Vitamin C. But it also allows Vitamin C quickly and easily enter your bloodstream to fuel your immune cells.

Epishield Plus

Epishield Plus

Ingredients Vitamin C, Vitamin D, Epicor, Mushroom Blend (Shiitake Mushroom, Cordyceps Sinensis powder, Reishi mushroom, and Maitake mushroom powder), Cellulose, Vegetable Magnesium Stearate, Silicon Dioxide
  • Reduces the risk of upper respiratory tract infections and supports overall sinus health
  • It helps to maintain a healthy and robust immune system
  • Promotes a healthy digestive system
  • It keeps your bones and muscles healthy.
Price $49

Epishield Plus is a natural supplement that helps to keep your immune system strong. It is made of extracts that have been used for centuries to treat health problems such as high blood pressure, asthma, sinusitis, and other respiratory issues.

According to the makers, this formula starts working in two hours and contains unique fermented yeast ingredients for enhanced immune responses.

Advanced Bionutritionals Resistol

Advanced Bionutritionals Resistol

Ingredients Platycodon, Eleuthero, Andrographis, Prickly Chaff Flower, and Licorice
  • All ingredients present in the supplement are known to boost immunity
  • Increases the activity of immune cells to boost energy and support the lymphatic system
  • It promotes healthy respiration and reduces the risk of respiratory infections
  • Support healthy inflammatory response and lung function.
Price $29.95

Advanced Bionutritionals Resistol uses the five herbs featured in the formula that have been studied for their positive effects. Many take them daily for their benefits and immune response. In scientific studies, Andrographis has been shown to support healthy immunity. Eleuthero root also helps the lymphatic system, which prevents infections and inflammations in the body.

Unlike other immune boosters, they utilize herbs and Poland extracts rather than straight vitamins. Resistol is among the most effective and affordable supplements for immune support.

Organixx 7M+

Organixx 7M+

Ingredients Organic Turkey Tail Mushroom, Organic Chaga, Organic Shiitake Mushroom, Organic Maitake, Organic Cordyceps, Organic Lion’s Mane, and Organic Reishi Mushroom
  • Reduces the high level of inflammation in the body
  • It helps to support a robust immune response
  • Improve energy levels and physical activity
  • Support healthy blood pressure, Blood sugar level, and digestion.
Price $54.95.

Functional mushrooms are nature’s medicinal cornucopia of healing. Not only do mushrooms contain critical nutrients like vitamin D and minerals, but they also can heal the body. The healing benefits of adding mushroom extracts into your daily life can significantly impact your overall wellness.

Organixx 7M+ contains a proprietary blend of 7 medicinal mushrooms known to promote immunity and anti-aging properties. According to the makers of Orgainxx 7M+, the formula will enhance brain function, gut health, and immune responses.

Using the adaptogenic-driven fermentation process in 7M+, the Organixx functional mushroom blend in 7M offers enhanced bioavailability.

BioShield MD

BioShield MD

Ingredients Quercetin, Elderberry Extract, Curcumin Extract, Cocoa Extract, Boswellia Serrata, Resveratrol, Green Tea Extract, and Immunity Complex (Vitamin C, Vitamin D, and Iron).
  • Support immune health and overall wellness
  • Ensure normal and healthy breathing
  • Support balanced inflammatory response
  • Enhance joint health and improve energy levels.
Price $49.95.

BioShield MD is created with seven potent flavonoids that support immune health in a better way, especially in times of stress and challenge. It is a go-to formula in cold and flu season for help with breathing and blood circulation.

Along with antioxidants and anti-inflammatory ingredients, the supplement contains a unique element that ensures you get adequate sleep and live a healthy life.

Additionally, BioShield MD reduces soreness after movements. Furthermore, they can assist the body in producing the collagen and extracellular proteins needed to maintain joint health.

VitaPost Turmeric & Ginger

VitaPost Turmeric & Ginger

Ingredients Turmeric, Ginger, Curcuminoids, and Bioperine.
  • Support immunity by raising immune cells
  • Support joint and muscle health
  • Improve respiratory function
  • Relieve the symptoms of certain infections and influenza virus
Price $23.95

With VitaPost Turmeric & Ginger, you can stay on top of your health daily. It features a balanced blend of turmeric and ginger, plus bioavailability-enhancing BioPerine. This combination of three ingredients provides many health benefits, including support for immunity and antioxidant protection.

Immuno Defense 4x

Immuno Defense 4x

Ingredients Quercetin, Vitamin D, Bromelain, and Whole Food Fermentate (EpiCor)
  • Increases T cells and antibodies
  • Reduce chronic inflammation
  • Improve respiration and breathing
  • Restrict pathogens and viruses.
Price $44.95

Immuno Defense 4x is a product brought to you by JayLab Pro, which is known for the quality product provided. All the ingredients are sourced from the specific areas where these are harvested organically. The supplement includes potent ingredients that activate the enzymes that uplift the immunity to a certain extent needed by your body.

Immuno Defense 4x, as the name suggests, is a miraculous dietary formula that helps you boost your immunity through various potent ingredients in a natural way. It is essential to have built a shield to protect your body from deadly diseases and other virus attacks.

Food Items to Support Immune Health

Here are certain food items that you must add to your daily diet to support immunity:

Citrus Fruits

Citrus fruits are a good source of vitamin C, essential for healthy immune function. Berries such as strawberries and raspberries are also good sources of vitamin C.

Red Bell Peppers

Red bell peppers are a great source of vitamin A, C, vitamin K, and dietary fiber. These nutrients can help strengthen the immune system and its function. As vitamin A contributes to healthy vision and immune system function, everyone needs to include red bell peppers in their diet.


Ginger is a popular herb used in traditional Chinese medicine for centuries. Its properties have been studied extensively, and it is known to support immune health in several ways. Its antioxidant compounds are also known to have anti-inflammatory properties, making ginger a healthy addition to diets looking to boost immunity.

Sunflower Seeds

Sunflower seeds are a great source of nutrients and antioxidants, which can help improve your immune system. In addition to fighting harmful bacteria and viruses, sunflower seeds can provide essential fatty acids, vitamins, minerals (including vitamin E), fiber, and anti-inflammatory compounds.


Get your poultry nutrients from a balanced diet. Include poultry in your regular rotation of food items to get the essential nutrients and healthy fats that can support your immunity and overall health.

Finally, ensure you eat nutritious foods like plenty of fruits, vegetables, and whole grains to support your immune health.


Yogurt is an excellent source of probiotics, which help support immune health. Yogurt contains calcium and vitamin D, essential nutrients for strong bones and healthy teeth. Probiotics in yogurt have been shown to reduce inflammation in the gut, leading to improved immune function and overall healthy digestion.

Sweet Potatoes

Sweet potatoes are an excellent source of beta carotene, vitamins C and E, potassium, fiber, and other essential nutrients. They also have anti-inflammatory properties that can help improve your immunity.

They’re also a good source of antioxidants, which can help protect the body against damage caused by free radicals.

Top Vitamins to Support Immune Health

Let us now understand how specific vitamins play an essential role in better immune system function:

Vitamin C

Vitamin C helps support the immune response by helping to prevent infection. It is also vital for synthesizing collagen, which is essential for healthy skin and bones. Collagen is a critical component of healthy connective tissues in the body, including blood vessels and gums. It can be found in many fruits and vegetables, so getting this vital vitamin into your diet is effortless.

Vitamin D

Vitamin D is essential for immunity. It helps stimulate immune health and regulates response to infections. Vitamin D deficiency is common in people living in colder climates, which can lead to an increased risk of disease.


Zinc is an essential mineral for healthy immune function. It helps to fight off infection and shield the body from damage caused by viruses, bacteria, and other pathogens. Zinc also helps heal wounds and protect the skin from sun exposure. Zinc deficiency can lead to an increased susceptibility to colds and other infections.


Curcumin is a yellow-orange-colored compound found in the spice turmeric. It has anti-inflammatory and antioxidant properties and is believed to help support immunity in various ways. This includes supporting white blood cell function and immunity and helping the body fight against infections.

Vitamin B6

Curcumin is a powerful antioxidant that can help protect the body against the harmful effects of free radicals. These are unstable molecules in the body and can damage cells, causing inflammation and other health problems. Vitamin B6 is essential for the body to produce curcumin so deficiencies can lead to health problems.


Elderberry is a popular choice for supporting immunity because it contains antioxidant flavonoids called anthocyanins, which are thought to boost the production of white blood cells, which help defend the body against infections and disease. Elderberry is also a good source of fiber, which can help regulate bowel movements and promote healthy digestion. It is also a good source of vitamin C, which allows the body to fight off infection and ward off colds and other illnesses.


Probiotics are beneficial bacteria that support your immune system. – They can boost your immune system by increasing the good bacteria in your gut. This can help improve the digestive system function and support skin and hair health. Taking probiotics regularly can help to maintain immune health. They may help to prevent some illnesses, such as flu infection or irritable bowel syndrome.

The Best Immunity Boosters for 2023 Conclusion

Besides supporting your immune system, vitamin supplements have been shown to help boost overall health and metabolism. Eating vitamin-rich foods and taking supplements is the best way to get the nutrients your body needs to function optimally. But if that’s not possible, supplementing with vitamin supplements can help support your immune system function healthily.

You can choose any of the above-stated immune boosters to enhance immune health naturally.


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The links contained in this product review may result in a small commission if you opt to purchase the product recommended at no additional cost to you. This goes towards supporting our research and editorial team. Please know we only recommend high-quality products.


Please understand that any advice or guidelines revealed here are not even remotely substitutes for sound medical or financial advice from a licensed healthcare provider or certified financial advisor. Make sure to consult with a professional physician or financial consultant before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary and are not guaranteed as the statements regarding these products have not been evaluated by the Food and Drug Administration or Health Canada. The efficacy of these products has not been confirmed by FDA, or Health Canada approved research. These products are not intended to diagnose, treat, cure or prevent any disease and do not provide any kind of get-rich money scheme. Reviewer is not responsible for pricing inaccuracies. Check product sales page for final prices.

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